Asklepios BioPharmaceutical, Inc. (AskBio) is a leading, clinical-stage gene therapy company founded in 2001 based on the work of adeno-associated virus (AAV) gene therapy visionary and pioneer, Jude Samulski, PhD. Since that time, our commitment to developing life-saving medicines that can potentially cure genetic diseases has never wavered.

At AskBio, we’ve built a foundation of therapeutic programs, AAV manufacturing and a rich portfolio of patented technology. Our therapeutic focus includes neuromuscular, central nervous system, cardiovascular and metabolic diseases with clinical trials underway for Pompe disease, Parkinson’s disease, and congestive heart failure. Our gene therapy platform includes Pro10™, an industry-leading proprietary cell line manufacturing process, and an extensive AAV capsid and promoter library.

We became a wholly-owned, independently operated, subsidiary of Bayer AG in late 2020 as a cornerstone of its newly formed Cell & Gene Therapy (CGT) platform. Our global headquarters is in Research Triangle Park, NC. Additionally, we have significant operations in Philadelphia, PA, Columbus, OH, Scotland, France, Germany, and Spain.

Our vision: Pioneering science to create transformative molecular medicines.

Our mission: Lead innovative science and drive clinical outcomes to transform people's lives.

Our Principles

Advance innovative science by pushing boundaries.
Bring transformative therapeutics to patients in need.
Provide an environment for employees to reach their fullest potential.

Our Values

Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.
Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.
Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.
Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.
Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.

Position Summary

AskBio is seeking a highly motivated, enthusiastic and collaborative Intern in Gene Editing to help us develop next-generation gene therapies. The Intern will support the Gene Editing team’s preclinical efforts and interface with teams across the R&D organization. The ideal candidate would have experience with mammalian cell culture and molecular biology techniques, such as DNA, RNA, and protein extraction, quantitative PCR, RT-PCR, ddPCR, ELISA, Western Blot, and next generation sequencing. Direct experience in gene therapy and gene editing research is desirable; however, prior experience is not required.

The internship will be located in RTP, North Carolina and will report to a Principal Scientist, Gene Editing.

Job Responsibilities

Perform relevant molecular- and cell-based assays to support therapeutic programs. This includes, but is not limited, to: DNA, RNA, and protein purification, AAV transduction, transfection, immunofluorescent staining, digital droplet PCR (ddPCR), Western blotting, and deep sequencing
Aid in novel assay development
Perform sample processing to support preclinical studies
Maintain an organized laboratory notebook and author timely reports detailing experimental work
Perform data analysis and communicate findings to research teams
Maintain reagent inventories and/or place orders for materials needed for assigned projects
Complete required training and contribute to efforts to maintain a safe and well-functioning laboratory environment.

Minimum Requirements

Must be at least a Junior pursuing a BS/BA degree in molecular or cellular biology, biomedical engineering, biochemistry, or related field at the time of application
Hands-on laboratory experience in biomedical research (at least 1 year)
Excellent technical skills with attention to detail
Excellent verbal and written communication skills
Self-starter with ability to multitask multiple projects and work independently
Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint)

Preferred Education, Experience And Skills

Those currently pursuing a MS or PhD are encouraged to apply.
Prior research experience with AAV gene therapy and gene editing technologies, such as CRISPR/Cas.
Proficient in mammalian cell culture, specifically with iPSC-derived cells
Proficient in molecular biology techniques, such as PCR, Western blotting, and next generation sequencing
Experience with ELISA or MSD-based assays
Experience with common laboratory software (ex. GraphPad, SnapGene) and use of an electronic notebook.

Asklepios BioPharmaceutical, Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email at careers@askbio.com.

Agencies: Please do not contact any employee at AskBio about this requisition. Any resume submitted by a recruitment agency to any employee at AskBio, through any medium, will be deemed the sole property of AskBio unless the agency was engaged by AskBio Talent Acquisition team to recruit for that position. All agencies must have a prior executed service agreement with AskBio prior to any search engagement. If a candidate who was submitted outside of the AskBio agency process is hired by AskBio, no fee or payment of any kind will be paid to the agency.

Askbio Inc. jobs

Intern- R&D Gene Editing