At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function

Discovery & Pre-Clinical/Clinical Development

Job Sub Function

Pharmacokinetics & Pharmacometrics

Job Category

Scientific/Technology

All Job Posting Locations:

Spring House, Pennsylvania, United States of America

Job Description

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for Senior Principal Scientist, Discovery Bioanalytical Strategy Lead in Spring House, PA.

Purpose: We are seeking a forward-thinking, scientifically adept Senior Principal Scientist to drive our Discovery Bioanalytical Strategy Lead role across the global JJIM portfolio. This strategic role will manage the integration of bioanalytical approaches—both in vitro and in vivo—across all therapeutic modalities, aligning with discovery objectives and enabling seamless transitions into development. The successful candidate will lead the progression of bioanalytical capabilities through combining advanced technical applications and deep discovery strategies while working globally with team leaders to incorporate scientifically relevant and right-sized solutions in a non-regulated environment. Their leadership will help optimize workflows, enhance data-driven decision-making, and accelerate the pace and precision of drug discovery. Serving as a critical bridge between global discovery bioanalytical teams and key stakeholders in BDDS and PSTS, this individual will ensure that bioanalytical project strategy is tightly aligned with scientific needs across functions—ultimately driving faster transitions from discovery to development and improving speed to clinic.

You Will Be Responsible For

Strategic Integration & Leadership:

Serve as central point-of-contact for BDDS discovery project teams and manage assignments for discovery team-facing roles and transition to downstream BDDS development team.
Develop and execute bioanalytical strategy that aligns with project team needs and drug discovery goals, emphasizing urgency, priority, and fit-for-purpose approaches.
Serve as a thought leader on modality strategy and innovation across the global discovery bioanalysis teams, including data science integration, emerging technologies, and strategic harmonization.
Lead the maintenance and optimization of resource tracking system to enable efficient bioanalytical support for modality-agnostic discovery programs across discovery portfolio.
Align strategic vision to deploy digital data tools and new alternative methodology (NAM) workflows across discovery bioanalytical labs supporting discovery and preclinical projects.
Provide informed discovery project and milestone updates (i.e. lead selection, NME-readiness, etc.) to BDDS LT

Cross-Functional Collaboration

Collaborate with key stakeholders (e.g. therapeutics discovery, PSTS, and therapeutic areas) to ensure bioanalytical approaches support modality and candidate selection to drive to NME readiness
Act as a primary liaison between discovery bioanalysis team leaders and discovery project teams to ensure bioanalytical strategy for internal lab-based activities.
Serve as primary interface with downstream BDDS functions including BA strategy transition and transfer to internal development teams as well as partner with BA outsourcing and portfolio management teams.
Collaborate with PSTS leaders and internal BA teams to enable implementation of workflows and analytical capabilities supporting new alternative methodologies (NAMs) in the discovery and preclinical setting.
Partner with data science teams to drive model-informed scalable infrastructure for real-time data access, visualization, and decisional project support.

Qualifications/Requirements

Education: Minimum of a Master’s Degree in Analytical Chemistry, Pharmaceutical Sciences or related field is required. PhD or PharmD is preferred.

Skills/Experience

Minimum of 8+ years of experience in drug discovery within the pharmaceutical or biotech industry.
Strong scientific background and understanding regarding implementation of bioanalytical strategy based on project or modality-specific requirements.
Thorough understanding of drug discovery process across therapeutic modalities.
Proven track record with development and execution of advanced bioanalytical techniques to address critical questions related to pharmacokinetics, pharmacodynamics, and ADME
Deep expertise in analytical or bioanalytical platforms, e.g. mass spec, nano/micro LC, QPCR, ligand binding assays.
Strong understanding of lab automation and digital platforms in life sciences.
Proven ability to lead cross-functional strategies and manage complex, multi-site initiatives.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource.

Johnson & Johnson Innovative Medicine jobs

Senior Principal Scientist, Discovery Bioanalytical Strategy Lead