Senior Vice President, Drug Design and Preclinical Development

About Generate:Biomedicines

Generate:Biomedicines is a new kind of therapeutics company – existing at the intersection of machine learning, biological engineering, and medicine – pioneering Generative Biology™ to create breakthrough medicines where novel therapeutics are computationally generated, instead of being discovered. The Company has built a machine learning-powered biomedicines platform with the potential to generate new drugs across a wide range of biologic modalities. This platform represents a potentially fundamental shift in what is possible in the field of biotherapeutic development.

We pursue this audacious vision because we believe in the unique and revolutionary power of generative biology to radically transform the lives of billions, with an outsized opportunity for patients in need. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!

Generate:Biomedicines was founded in 2018 by Flagship Pioneering and has received over $700 million in funding, providing the resources to rapidly scale the organization. The Company has offices in Somerville and Andover, Massachusetts with over 300 employees.

The Role:

Generate:Biomedicines is seeking an innovative and experienced visionary Senior Vice President, Drug Design and Preclinical Development to lead and revolutionize the development of new medicines using Generate:Biomedicines’ cutting edge platform. This role is pivotal in driving forward our unique approach to drug development, deploying both innovative and proven methods to define and advance a pipeline of first- and best-in-class biologics. The ideal candidate will bring significant expertise in protein sciences, protein engineering and drug discovery, together with experience in and enthusiasm for the application of computational and digital approaches to all aspects of drug development.

Given the breadth of the applicability of the company’s technology, the role will manage a complex and broad pipeline of research programs and must be comfortable defining the path for a diverse set of molecules from concept through Phase 1. This executive will have an established level of respect and credibility in the research and development community. They must bring a strong entrepreneurial orientation along with stellar leadership skills and an enthusiasm about developing new methods across functions. The executive will be a member of the Research and Development Leadership Team and the Senior Leadership Team, and will report to the Head of R&D. The role will oversee critical functions within Generate, including all protein science and preclinical functions.

Join us at Generate:Biomedicines, where your leadership will not only shape the future of medicine but also inspire a culture of innovation and discovery that transcends the traditional boundaries of biotechnology.

Here's how you will contribute:

The Senior Vice President, Drug Design and Preclinical Development will be responsible for the following:

• Formulate preclinical research strategy, including development and execution of Generate:Biomedicines’s R&D roadmap in partnership with the Head of R&D and the Head of Computational Sciences
• Foster the mutually beneficial development of the platform and portfolio, ensuring advancement of portfolio molecules to the clinic
• Develop a deep understanding of the computational, protein sciences and assays at the Company; unify the involved scientists around a vision for creative and timely advancement of our methods
• Apply an engineering mindset to the productionization of drug development
• Scientific thought leadership, including mentorship of and providing a role model to scientists throughout the organization
• Apply expertise in protein sciences, protein engineering, automation and high-throughput data generation to the platform and to pipeline programs
• Identify, evaluate and translate the latest global scientific and technology developments in academia and industry for the company
• Ensure swift and high-quality execution of research strategy, including dynamic prioritization and trade-offs across a myriad of programs and platform initiatives
• Effectively manage resources/budget with agility to maximize value creation
• Build a diverse, high-performing organization and culture of innovation and execution
• Foster a work environment that encourages creative thinking and the ability maintain focus, persistence and agility in the setting of continuous change and, at times, adversity
• Develop and nurture effective cross-functional relationships across the organization
• Serve as a leading scientific spokesperson for Generate:Biomedicines and effectively represent the company both internally and externally within the scientific, medical and business communities
• Support Generate:Biomedicines’s IP, M&A and licensing activities as needed
  
  

The Ideal Candidate will have:

• PhD, MD or MD/PhD degree in scientific discipline
• 15+ years of leadership experience in the biopharmaceutical industry, including experience at the junction of computation and protein sciences
• Technical expertise and strategic/transformational leadership
• Experience in leveraging cutting-edge technologies for biological discovery and drug development
• The ability to consider and debate both deep technical and broad strategic issues
• Skilled at inspiring, building and developing high-performing teams of scientists
• History of successful people management, including attracting and retaining highly qualified world-class talent
• Drive for achievement; results-oriented, active, hands-on manager
• Sound business judgement able to continuously evaluate priorities, alternatives efficient resource management
• Strong external presence in the research community
  
  

Location: Somerville, MA

Generate:Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

COVID Safety:

Generate:Biomedicines enforces a mandatory vaccination policy for COVID-19. All employees must be fully vaccinated and have received a booster. The purpose of this policy is to safeguard the health of our employees, their families, and the community at large from infectious disease that may be reduced by vaccinations. The Company will make exceptions to this policy if required by applicable law and will consider requests for an exemption from this policy due to a medical reason, or because of a sincerely held religious belief, or any other exemptions that may be recognized by applicable.

Recruitment & Staffing Agencies : Generate:Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Generate:Biomedicines or its employees is strictly prohibited unless contacted directly by the Company’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Generate:Biomedicines and the Company will not owe any referral or other fees with respect thereto.